Click on a game below to view boxscore.
| Overall | Conference | |
|---|
| Date | Opponent | Score | Record | Record | Win | Loss | Save |
|---|
| February 19, 2010 |  vs Kentucky | L | 6-15 | 0-1 | - | Alex Meyer | Justin Wright | |
| February 20, 2010 |  at (12) Coastal Carolina | L | 5-13 | 0-2 | - | Matt REIN | Mathew Price | |
| February 21, 2010 |  vs West Virginia | W | 14-3 | 1-2 | - | Jesse Hahn | Jared HILL | |
| February 26, 2010 |  at Charleston Southern | W | 17-2 | 2-2 | - | Justin Wright | Jesse CADENHEAD | |
| February 27, 2010 | at Charleston Southern | W | 4-2 | 3-2 | - | Jesse Hahn | Charlie McCREADY | Ben Rowen |
| February 28, 2010 | at Charleston Southern | W | 13-1 | 4-2 | - | Joe Mantiply | Tyler THORNBURG | |
| March 5, 2010 |  LIU BROOKLYN | W | 9-2 | 5-2 | - | Justin Wright | Kenny CEDEL | |
| March 6, 2010 | LIU BROOKLYN | W | 6-0 | 6-2 | - | Jesse Hahn | Matt McCORMICK | |
| March 6, 2010 | LIU BROOKLYN | W | 11-0 | 7-2 | - | Joe Mantiply | Adam SAUTER | |
| March 7, 2010 | LIU BROOKLYN | W | 12-4 | 8-2 | - | Mathew Price | Justin TOPA | |
| March 9, 2010 |  BRYANT | W | 5-4 | 9-2 | - | Ben Rowen | JOHN MICHAEL RYAN | |
| March 10, 2010 | BRYANT | L | 3-5 | 9-3 | - | Peter KELICH | Patrick Scoggin | Mark ANDREWS |
| March 12, 2010 |  MARYLAND * | L | 0-10 | 9-4 | 0-1 | Brett Harman | Justin Wright | |
| March 13, 2010 | MARYLAND * | W | 13-4 | 10-4 | 1-1 | Jesse Hahn | Eric Potter | |
| March 14, 2010 | MARYLAND * | W | 8-4 | 11-4 | 2-1 | Mathew Price | Ian Schwalenberg | |
| March 15, 2010 |  COLUMBIA | W | 22-10 | 12-4 | - | Jake Joyce | Harrison Slutsky | |
| March 16, 2010 |  RIDER | W | 11-8 | 13-4 | - | Brandon Fisher | Nate Eppley | Ben Rowen |
| March 17, 2010 | RIDER | L | 6-10 | 13-5 | - | Chris Taylor | Manny Martir | |
| March 19, 2010 |  at (7) Clemson * | L | 0-3 | 13-6 | 2-2 | Casey Harman | Justin Wright | David Haselden |
| March 20, 2010 | at (7) Clemson * | L | 2-5 | 13-7 | 2-3 | Will Lamb | Jesse Hahn | Alex Frederick |
| March 20, 2010 | at (7) Clemson * | L | 8-13 | 13-8 | 2-4 | Scott Weismann | Joe Mantiply | Jonathan Meyer |
| March 24, 2010 |  LIBERTY | W | 10-0 | 14-8 | - | Manny Martir | Dustin UMBERGER | |
| March 26, 2010 |  WAKE FOREST * | W | 7-0 | 15-8 | 3-4 | Justin Wright | Michael Dimock | |
| March 27, 2010 | WAKE FOREST * | L | 0-5 | 15-9 | 3-5 | Tim Cooney | Jesse Hahn | |
| March 27, 2010 | WAKE FOREST * | W | 2-1 | 16-9 | 4-5 | Mathew Price | Austin Stadler | |
| March 30, 2010 |  (29) VMI | W | 11-3 | 17-9 | - | Manny Martir | Coby COWGILL | |
| March 31, 2010 |  at East Tennessee State | W | 14-3 | 18-9 | - | Patrick Scoggin | Josh MEANS | |
| April 2, 2010 |  at (4) Florida State * | W | 10-5 | 19-9 | 5-5 | Justin Wright | Sean Gilmartin | |
| April 3, 2010 | at (4) Florida State * | W | 8-7 | 20-9 | 6-5 | Mathew Price | John Gast | Ben Rowen |
| April 4, 2010 | at (4) Florida State * | L | 6-9 | 20-10 | 6-6 | Daniel Bennett | Manny Martir | Mike McGee |
| April 6, 2010 |  NORTH CAROLINA CENTRAL | W | 13-0 (7) | 21-10 | - | Joe Parsons | Glenn FRYE | |
| April 9, 2010 |  (9) MIAMI * | W | 9-7 | 22-10 | 7-6 | Ben Rowen | Eric Whaley | |
| April 10, 2010 | (9) MIAMI * | L | 2-9 | 22-11 | 7-7 | Eric Erickson | Mathew Price | |
| April 11, 2010 | (9) MIAMI * | W | 4-2 | 23-11 | 8-7 | Jesse Hahn | Jason Santana | Ben Rowen |
| April 13, 2010 |  NORTH CAROLINA A&T | W | 5-1 | 24-11 | - | Brandon Fisher | OELKER,Nick | |
| April 16, 2010 |  at (1) Virginia * | L | 2-4 | 24-12 | 8-8 | Tyler Wilson | Ben Rowen | Kevin Arico |
| April 17, 2010 | at (1) Virginia * | L | 2-8 | 24-13 | 8-9 | Robert Morey | Mathew Price | Tyler Wilson |
| April 18, 2010 | at (1) Virginia * | W | 8-5 | 25-13 | 9-9 | Ben Rowen | Kevin Arico | |
| April 20, 2010 |  at Radford | W | 16-6 | 26-13 | - | Manny Martir | Paul DeVITO | |
| April 23, 2010 |  at (3) Georgia Tech * | W | 3-1 (11) | 27-13 | 10-9 | Ben Rowen | Ben McKinney | |
| April 24, 2010 | at (3) Georgia Tech * | W | 10-3 | 28-13 | 11-9 | Mathew Price | Brandon Cumpton | |
| April 25, 2010 | at (3) Georgia Tech * | L | 12-14 | 28-14 | 11-10 | Jed Bradley | Marc Zecchino | Luke Bard |
| April 27, 2010 | at VMI | W | 9-2 | 29-14 | - | Joe Mantiply | Jeremy BROWN | |
| April 30, 2010 |  BOSTON COLLEGE * | W | 9-4 | 30-14 | 12-10 | Justin Wright | Mike Dennhardt | |
| May 1, 2010 | BOSTON COLLEGE * | W | 3-1 | 31-14 | 13-10 | Mathew Price | Pat Dean | |
| May 2, 2010 | BOSTON COLLEGE * | W | 10-5 | 32-14 | 14-10 | Sean McDermott | John Leonard | |
| May 4, 2010 |  DAVIDSON | L | 10-14 | 32-15 | - | Thomas Middour | Manny Martir | |
| May 8, 2010 |  SAVANNAH STATE | W | 12-0 | 33-15 | - | Justin Wright | ALLEGRETTI,Michael | |
| May 9, 2010 | SAVANNAH STATE | W | 7-0 | 34-15 | - | Mathew Price | SHERROD,Mark | Ben Rowen |
| May 14, 2010 |  DUKE * | W | 11-3 | 35-15 | 15-10 | Justin Wright | Marcus Stroman | |
| May 15, 2010 | DUKE * | W | 18-8 | 36-15 | 16-10 | Marc Zecchino | Eric Pfisterer | |
| May 16, 2010 | DUKE * | L | 7-11 | 36-16 | 16-11 | Dennis O'Grady | Jesse Hahn | |
| May 20, 2010 |  at (26) North Carolina * | L | 6-13 | 36-17 | 16-12 | Matt Harvey | Justin Wright | |
| May 21, 2010 | at (26) North Carolina * | L | 3-5 | 36-18 | 16-13 | Colin Bates | Sean McDermott | |
| May 22, 2010 | at (26) North Carolina * | L | 2-10 | 36-19 | 16-14 | Patrick Johnson | Jesse Hahn | |
| May 27, 2010 | vs (6) Georgia Tech | W | 6-2 | 37-19 | - | Justin Wright | Deck McGuire | |
| May 28, 2010 | vs (16) Clemson | W | 9-8 | 38-19 | - | Ben Rowen | Kevin Kyle | |
| May 29, 2010 |  vs NC State | L | 9-10 (10) | 38-20 | - | Jake Buchanan | Ben Rowen | Grant Sasser |
| June 4, 2010 |  vs (30) The Citadel | L | 2-7 | 38-21 | - | Matt Talley | Justin Wright | |
| June 5, 2010 |  vs Bucknell | W | 16-7 | 39-21 | - | Manny Martir | Trey Frahler | |
| June 6, 2010 | vs (30) The Citadel | W | 4-3 | 40-21 | - | Joe Mantiply | Michael Clevinger | Ben Rowen |
| June 6, 2010 |  (8) SOUTH CAROLINA | L | 2-10 | 40-22 | - | Jose Mata | Mathew Price | |
| * - Conference Game |
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