| Date | VT Rank | Opponent | Result | TV | Location |
|---|---|---|---|---|---|
| Sat., Oct 6, 1900 | St. Albans | W, 21-0 | Blacksburg, Va. | ||
| Sat., Oct 20, 1900 | at St. Albans | W, 16-6 | Radford, Va. | ||
| Thu., Oct 25, 1900 | at NC State | W, 18-2 | Raleigh, N.C. | ||
| Sat., Oct 27, 1900 | at North Carolina | T, 0-0 | Chapel Hill, N.C. | ||
| Wed., Nov 14, 1900 | at Virginia | L, 5-17 | Charlottesville, Va. | ||
| Sat., Nov 24, 1900 | vs. Clemson | L, 5-12 | Charlotte, N.C. | ||
| Sun., Nov 25, 1900 | vs. VMI | L, 0-5 | Roanoke, Va. |
| Overall: 3-3-1 Conference: 0-0 Home: 1-0 Away: 2-1-1 Neutral: 0-2 |
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