| Date | VT Rank | Opponent | Result | TV | Location |
|---|---|---|---|---|---|
| Sat., Sep 21, 1968 | vs. #7 Alabama | L, 7-14 | Birmingham, Ala. | ||
| Sat., Sep 28, 1968 | at William & Mary | W, 12-0 | Williamsburg, Va. | ||
| Sat., Oct 5, 1968 | Kansas State | L, 19-34 | Blacksburg, Va. | ||
| Homecoming | |||||
| Sat., Oct 12, 1968 | Wake Forest | W, 7-6 | Blacksburg, Va. | ||
| Fri., Oct 18, 1968 | at #12 Miami | L, 8-13 | Miami, Fla. | ||
| Sat., Oct 26, 1968 | West Virginia | W, 27-12 | Blacksburg, Va. | ||
| Sat., Nov 2, 1968 | at #18 Florida State | W, 40-22 | Tallahassee, Fla. | ||
| Sat., Nov 9, 1968 | Richmond | W, 31-18 | Blacksburg, Va. | ||
| Sat., Nov 16, 1968 | at South Carolina | W, 17-6 | Columbia, S.C. | ||
| Thu., Nov 28, 1968 | vs. VMI | W, 55-6 | Roanoke, Va. | ||
| Liberty Bowl | |||||
| Sat., Dec 14, 1968 | vs. Mississippi | L, 17-34 | ABC (national) | Memphis, Tenn. | |
| Overall: 7-4 Conference: 0-0 Home: 3-1 Away: 3-1 Neutral: 1-2 |
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